Abstract With the growth of clinical cancer single-cell RNA sequencing studies, robust differential expression methods for case/control analyses (e.g., treatment responders vs.non-responders) using gene signatures are pivotal to nominate hypotheses for further investigation.However, many commonly used methods produce a large number of false positiv
Internet interconnection infrastructure: lessons from the global South
This article examines the formation of the first internet exchange point (IXP) in Mexico amid the implementation of telecommunication reforms and asymmetric regulations in a market with low level of competition.An IXP is defined as a shared interconnection facility and Laminate a key internet governance arena where players with myriad goals and fun
Mesoaortic entrapment of a left inferior vena cava
A persistent left inferior vena cava (IVC) is a rare anomaly, with a reported incidence of only 0.2-0.5%.When present, it courses between the superior mesenteric artery and the aorta to continue as the right IVC, similar to the course of a left renal vein (LRV).This anomaly is usually asymptomatic, but there may be vague abdominal complaints
Human Behavior During Emergency Evacuation: Cell Transmission Model
This paper presents an extended cell transmission model to simulate an emergency evacuation of crowd in a supermarket scenario.The supermarket scenario with a daily shopping, an emergency exit and multiple parallel shelves is discretized into a set of regular hexagonal cells.First, we verify the validity of the model by comparing the results of the